Philadelphia, Pennsylvania

With its storied history, diverse neighborhoods, and superb culinary scene, Philadelphia has always been a popular American travel destination. But more visitors than ever are making the trip to the City of Brotherly Love. In 2011, Philly saw a record number of travelers (38 million, to be exact) pour into the city. One of Philadelphia's biggest new draws is The Barnes Foundation, a world-class art gallery that relocated to the museum-packed Benjamin Franklin Parkway last May. Travel + Leisure called it "a game changer for Philadelphia, at a moment of splendid cultural renaissance."