Visitors to the Napa Valley are spoiled by choices when it comes to nearby airports. San Francisco International, Oakland International, and Sacramento International are all about an hour away. San Jose International is about a one-and-a-half hour drive from Napa. All of these airports are served by both major and low-cost airlines, a winning combination that keeps fares competitive.
The Napa Valley is about an hour from San Francisco. Most people drive to Napa from area airports or other nearby destinations. Driving to the region offers visitors more flexibility once they've arrived, but those who prefer to visit without a car can find an airport shuttle or limo service to the region, or can hop on a bus tour from San Francisco.
From San Francisco, the most dramatic and beautiful way to get to Napa is to go over the Golden Gate Bridge and up U.S. Highway 101. Though it's less scenic, visitors coming from the East Bay and those in a hurry may want to consider U.S. Highway 80 to Highway 37. For specific directions, use an online service such as Mapquest or Google Maps, or pick up a good old-fashioned map.