Here are more destinations to keep on the radar in 2010:

Hawaii: A bevy of new routes from Alaska (Sacramento and San Jose to Hawaii in March), Continental (Orange County to Honolulu starting March 7), and US Airways (Charlotte to Honolulu starting December 17, 2009) put Hawaii within reach of more travelers. Plus, Norwegian Cruise Line will add two more Hawaii cruises this spring.

Istanbul, Turkey: Istanbul celebrates its heritage and vitality as a 2010 European Capital of Culture. Throughout 2010, the city will feature music, literature, theater, traditional arts, and more.

Vancouver: Vancouver is mere months away from welcoming the world to the XXI Olympic Winter Games. For the rest of the year, take advantage of tourism infrastructure improvements without battling Olympic crowds.

Ft. Lauderdale: Both JetBlue and Virgin America have just started service between San Francisco and Ft. Lauderdale, making it easier to get to from the West Coast. Nearby Miami will host the Pro Bowl in January, and the Super Bowl in February, making Ft. Lauderdale a hot spot for sports fans around the country. Ft. Lauderdale is also the new home of the world's largest (for now) cruise ship, Royal Caribbean's Oasis of the Seas.

Capetown, South Africa: Another hot destination for sports enthusiasts in 2010, Cape Town will host the FIFA World Cup beginning in June.

Colombia: With Spirit increasing service to Colombia, and more low-cost carrier service from JetBlue, this up-and-coming destination is easier to get to than ever before.

Cuba: Will 2010 be the year the U.S. eases its travel ban on Cuba? It's certainly a destination to watch this coming year.

What other destinations should we keep an eye on in 2010? Share your ideas in the comments below!