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We found 91 matches for direct flights, non-stop flights, and last-minute flights between SAN and DSM. Use the table below to sort by number of connections or the time of day to find flights that leave SAN for DSM in the morning, afternoon, or evening.
Be sure to check our list of deals to see which airlines are offering special prices on airfare to Des Moines, IA (DSM) or airfare from San Diego, CA (SAN).
| Airline | Flt. | Departs | Time | Arrives | Time |
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| US Airways | 6100 | SAN | 6:20am | DSM | 12:53pm | Denver (DEN) | Search prices |
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| United Airlines | 484 | SAN | 6:20am | DSM | 12:53pm | Denver (DEN) | Search prices |
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| Frontier Airlines | 550 | SAN | 6:25am | DSM | 3:22pm | Denver (DEN) | Search prices |
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| US Airways | 6102 | SAN | 8:10am | DSM | 3:22pm | Denver (DEN) | Search prices |
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| US Airways | 6102 | SAN | 8:10am | DSM | 3:22pm | Denver (DEN) | Search prices |
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| United Airlines | 418 | SAN | 8:10am | DSM | 3:22pm | Denver (DEN) | Search prices |
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| United Airlines | 418 | SAN | 8:10am | DSM | 3:22pm | Denver (DEN) | Search prices |
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| Frontier Airlines | 558 | SAN | 11:00am | DSM | 6:08pm | Denver (DEN) | Search prices |
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| United Airlines | 342 | SAN | 11:20am | DSM | 6:08pm | Denver (DEN) | Search prices |
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| US Airways | 6104 | SAN | 11:20am | DSM | 6:08pm | Denver (DEN) | Search prices |
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| United Airlines | 342 | SAN | 11:20am | DSM | 6:08pm | Denver (DEN) | Search prices |
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| US Airways | 6104 | SAN | 11:20am | DSM | 6:08pm | Denver (DEN) | Search prices |
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| US Airways | 6106 | SAN | 2:55pm | DSM | 10:28pm | Denver (DEN) | Search prices |
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| United Airlines | 354 | SAN | 2:55pm | DSM | 10:28pm | Denver (DEN) | Search prices |
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| United Airlines | 354 | SAN | 2:55pm | DSM | 10:28pm | Denver (DEN) | Search prices |
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| US Airways | 6106 | SAN | 2:55pm | DSM | 10:28pm | Denver (DEN) | Search prices |
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| Frontier Airlines | 564 | SAN | 3:10pm | DSM | 10:28pm | Denver (DEN) | Search prices |
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| American Airlines | 322 | SAN | 6:20am | DSM | 2:45pm | Dallas (DFW) | Search prices |
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| American Airlines | 1564 | SAN | 7:40am | DSM | 4:25pm | Dallas (DFW) | Search prices |
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| American Airlines | 1914 | SAN | 8:40am | DSM | 4:25pm | Dallas (DFW) | Search prices |
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| American Airlines | 1914 | SAN | 8:40am | DSM | 5:50pm | Dallas (DFW) | Search prices |
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| American Airlines | 1454 | SAN | 9:45am | DSM | 5:50pm | Dallas (DFW) | Search prices |
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| American Airlines | 1046 | SAN | 1:00pm | DSM | 9:35pm | Dallas (DFW) | Search prices |
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| Continental Airlines | 132 | SAN | 6:45am | DSM | 4:40pm | Houston (IAH) | Search prices |
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| Continental Airlines | 1041 | SAN | 8:05am | DSM | 4:40pm | Houston (IAH) | Search prices |
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| Continental Airlines | 1588 | SAN | 12:35pm | DSM | 9:50pm | Houston (IAH) | Search prices |
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| Northwest Airlines | 1664 | SAN | 12:05pm | DSM | 8:08pm | Memphis (MEM) | Search prices |
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| Northwest Airlines | 1664 | SAN | 12:05pm | DSM | 8:08pm | Memphis (MEM) | Search prices |
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| Delta Air Lines | 2724 | SAN | 6:35am | DSM | 2:40pm | Minneapolis (MSP) | Search prices |
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| Delta Air Lines | 2724 | SAN | 6:35am | DSM | 2:40pm | Minneapolis (MSP) | Search prices |
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| Northwest Airlines | 186 | SAN | 6:35am | DSM | 2:40pm | Minneapolis (MSP) | Search prices |
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| Northwest Airlines | 186 | SAN | 6:35am | DSM | 4:26pm | Minneapolis (MSP) | Search prices |
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| Northwest Airlines | 186 | SAN | 6:35am | DSM | 4:26pm | Minneapolis (MSP) | Search prices |
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| Delta Air Lines | 2724 | SAN | 6:35am | DSM | 4:26pm | Minneapolis (MSP) | Search prices |
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| Delta Air Lines | 2724 | SAN | 6:35am | DSM | 4:26pm | Minneapolis (MSP) | Search prices |
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| Northwest Airlines | 186 | SAN | 6:35am | DSM | 2:40pm | Minneapolis (MSP) | Search prices |
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| Delta Air Lines | 2990 | SAN | 2:20pm | DSM | 11:01pm | Minneapolis (MSP) | Search prices |
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| Delta Air Lines | 2990 | SAN | 2:20pm | DSM | 11:01pm | Minneapolis (MSP) | Search prices |
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| Northwest Airlines | 188 | SAN | 2:20pm | DSM | 11:01pm | Minneapolis (MSP) | Search prices |
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| Northwest Airlines | 188 | SAN | 2:20pm | DSM | 11:01pm | Minneapolis (MSP) | Search prices |
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| Alaska Airlines | 1088 | SAN | 6:20am | DSM | 4:09pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1088 | SAN | 6:20am | DSM | 4:09pm | Chicago (ORD) | Search prices |
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| American Airlines | 1128 | SAN | 6:20am | DSM | 3:20pm | Chicago (ORD) | Search prices |
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| American Airlines | 1128 | SAN | 6:20am | DSM | 4:09pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1088 | SAN | 6:20am | DSM | 3:20pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1088 | SAN | 6:20am | DSM | 3:20pm | Chicago (ORD) | Search prices |
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| American Airlines | 1128 | SAN | 6:20am | DSM | 4:09pm | Chicago (ORD) | Search prices |
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| United Airlines | 16 | SAN | 6:30am | DSM | 3:20pm | Chicago (ORD) | Search prices |
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| US Airways | 6922 | SAN | 6:30am | DSM | 4:09pm | Chicago (ORD) | Search prices |
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| US Airways | 6922 | SAN | 6:30am | DSM | 4:09pm | Chicago (ORD) | Search prices |
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| United Airlines | 16 | SAN | 6:30am | DSM | 4:09pm | Chicago (ORD) | Search prices |
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| United Airlines | 16 | SAN | 6:30am | DSM | 4:09pm | Chicago (ORD) | Search prices |
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| US Airways | 6922 | SAN | 6:30am | DSM | 3:20pm | Chicago (ORD) | Search prices |
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| US Airways | 6150 | SAN | 8:30am | DSM | 6:07pm | Chicago (ORD) | Search prices |
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| United Airlines | 266 | SAN | 8:30am | DSM | 6:07pm | Chicago (ORD) | Search prices |
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| US Airways | 6150 | SAN | 8:30am | DSM | 6:07pm | Chicago (ORD) | Search prices |
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| United Airlines | 266 | SAN | 8:30am | DSM | 6:07pm | Chicago (ORD) | Search prices |
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| American Airlines | 1734 | SAN | 10:15am | DSM | 6:50pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1307 | SAN | 10:15am | DSM | 6:50pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1307 | SAN | 10:15am | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1307 | SAN | 10:15am | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| American Airlines | 1734 | SAN | 10:15am | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| American Airlines | 1734 | SAN | 10:15am | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1307 | SAN | 10:15am | DSM | 6:50pm | Chicago (ORD) | Search prices |
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| US Airways | 6926 | SAN | 11:15am | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| United Airlines | 845 | SAN | 11:15am | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| United Airlines | 845 | SAN | 11:15am | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| US Airways | 6926 | SAN | 11:15am | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1297 | SAN | 12:00pm | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1297 | SAN | 12:00pm | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1297 | SAN | 12:00pm | DSM | 9:44pm | Chicago (ORD) | Search prices |
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| American Airlines | 594 | SAN | 12:00pm | DSM | 9:44pm | Chicago (ORD) | Search prices |
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| American Airlines | 594 | SAN | 12:00pm | DSM | 9:44pm | Chicago (ORD) | Search prices |
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| American Airlines | 594 | SAN | 12:00pm | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| American Airlines | 594 | SAN | 12:00pm | DSM | 8:14pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1297 | SAN | 12:00pm | DSM | 9:44pm | Chicago (ORD) | Search prices |
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| US Airways | 6928 | SAN | 1:21pm | DSM | 9:44pm | Chicago (ORD) | Search prices |
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| US Airways | 6928 | SAN | 1:21pm | DSM | 9:44pm | Chicago (ORD) | Search prices |
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| United Airlines | 628 | SAN | 1:21pm | DSM | 9:44pm | Chicago (ORD) | Search prices |
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| United Airlines | 628 | SAN | 1:21pm | DSM | 9:44pm | Chicago (ORD) | Search prices |
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| United Airlines | 628 | SAN | 1:21pm | DSM | 11:05pm | Chicago (ORD) | Search prices |
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| US Airways | 6928 | SAN | 1:21pm | DSM | 11:05pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1021 | SAN | 2:45pm | DSM | 11:05pm | Chicago (ORD) | Search prices |
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| Alaska Airlines | 1021 | SAN | 2:45pm | DSM | 11:05pm | Chicago (ORD) | Search prices |
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| American Airlines | 1358 | SAN | 2:45pm | DSM | 11:05pm | Chicago (ORD) | Search prices |
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| US Airways | 511 | SAN | 6:30am | DSM | 1:50pm | Phoenix (PHX) | Search prices |
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| US Airways | 347 | SAN | 6:35am | DSM | 1:50pm | Phoenix (PHX) | Search prices |
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| US Airways | 351 | SAN | 9:50am | DSM | 4:47pm | Phoenix (PHX) | Search prices |
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| US Airways | 500 | SAN | 4:20pm | DSM | 11:40pm | Phoenix (PHX) | Search prices |
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| Delta Air Lines | 4856 | SAN | 3:05pm | DSM | 11:10pm | Salt Lake City (SLC) | Search prices |
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| Delta Air Lines | 4856 | SAN | 3:05pm | DSM | 11:10pm | Salt Lake City (SLC) | Search prices |
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DEN: Denver International Airport |
Alaska Airlines |
Disclaimer
Smarter Travel Media LLC and Innovata, LLC have used their best efforts to collect and prepare material for inclusion in this travel directory, and cannot warrant that the information is totally complete or accurate.
Data shown in this directory are for information only. Neither Innovata nor Smarter Travel Media LLC will be responsible for the failure of flights to operate at the times listed in this publication, nor for errors herein, nor for failure to make connections with planes, nor for any omissions of data.
Schedules are subject to change without notice. Schedules shown are based on expected flight times as presented to Smarter Travel Media LLC. Weather and other factors may affect operating conditions, and departures and arrivals cannot be guaranteed. The mileage shown is approximate, based on industry standards, and will vary from actual airline mileage received for each flight segment.
Smarter Travel Media LLC and Innovata disclaim any liability to any person for loss or damage caused by errors or omissions in the data contained on this page, whether such errors or omissions result from negligence, accident or other cause.
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